Ezina · A Field Manual for Plant Care · United States Vol. I · Ed. 2027 · Proof copy

§ Toxic plants · Berberidaceae · Checked Oct 2026

Is mayapple toxic to cats and dogs?

Yes. Mayapple (Podophyllum peltatum) is toxic to cats and dogs, according to the ASPCA Animal Poison Control Center. Plant Smart rates its effects Critical, level 4 of 4.

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Mayapple (Podophyllum peltatum)
Photo: no rights reserved, uploaded by mefisher, via iNaturalist

§ 010 · Signs

What to watch for

Signs include vomiting, diarrhea, lethargy, panting, coma, skin sores, skin irritation, belly pain, drooling, liver failure and bone marrow suppression. Signs can start within hours; some take a day or more to show.

§ 020 · If it happened

What to do if your pet ate it

Call your vet or a pet poison hotline straight away, even if your pet seems fine: the ASPCA Animal Poison Control Center, (888) 426-4435, or Pet Poison Helpline, (855) 764-7661. Both are open 24 hours and charge a fee. Have the plant or a photo of it to hand, and don’t make your pet vomit unless a vet tells you to.

§ 030 · Same family

Other Berberidaceae plants toxic to pets

Mayapple belongs to the Berberidaceae family. ASPCA lists these relatives too.

§ 040 · Questions

Questions about mayapple and pets

Is mayapple toxic to cats?

Yes. ASPCA lists mayapple as toxic to cats.

Is mayapple toxic to dogs?

Yes. ASPCA lists mayapple as toxic to dogs.

What happens if my pet eats mayapple?

Signs include vomiting, diarrhea, lethargy, panting, coma, skin sores, skin irritation, belly pain, drooling, liver failure and bone marrow suppression. Plant Smart rates it Critical, level 4 of 4.

What should I do if my pet ate it?

Call your vet or a pet poison hotline right away, even before signs appear: the ASPCA Animal Poison Control Center at (888) 426-4435, or Pet Poison Helpline at (855) 764-7661. Both charge a fee. Have the plant, or a photo of it, to hand.

Changes

5 Oct 2026: page drafted.

Sources

ASPCA Animal Poison Control Center: Toxic and Non-Toxic Plant List.

Plant Smart: Plant Smart: plants toxic to pets.

Photo: no rights reserved, uploaded by mefisher, via iNaturalist, source.

Checked Oct 2026.